|WHAT DO YOU NEED IN THE WAY OF VENTILATION?
Nearly all the materials used in automotive re-finishing are hazardous to your health, the paint especially so. The catalysts usually contain Di-isocyanate Prepolymer, and it's the that is the main concern. It attacks the central nervous system, and can cause permanent injury.
A good air flow, and a fresh air mask should be used. If you don't have any bronchial problems, then an activated charcoal mask can be used. I have used the charcoal mask for years, but now my lungs seem to have an asthmatic reaction to the fumes and I strictly use the fresh air system. Also, some paints contain lead, which may have negative effects on your health when painting or sanding.
Read and follow all label and MSDS instructions and observe all precautions supplied by the paint manufacturers. Click on AutoBodyDepot.net and then on MSDS for specifics.